OSTEOMED FORTE

OSTEOMED FORTE

Innovative vitamin & mineral complex for restoration and strengthening of bone tissue

Ingredients (500 mg):

— calcium citrate (250 mg);

— vitamin В6 (0.5 mg);

— vitamin D3, or cholecalciferol, a substance with activity 100000 IU/g (1.5 mg);

— organic anabolic component of natural origin — HDBA organic complex (glucose-adsorbed drone brood homogenate with vitamin В6) (50 mg).

Excipients: lactose, calcium stearate.

Composition of the homogenate:

— proteins (10–20 %);

— carbohydrates (1–5.5 %);

fats (5–6.3 %);

— glucose (3.18–5 %);

— fructose and saccharose  (up to 0.5 %);

— amino acids (11.4 %): lysine, histidine, arginine, aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, methionine, isoleucine, leucine, tyrosine, phenylalanine, cysteine;

— entomologic hormones that are precursors of human gonadal type hormones, or prohormones (nmol/100 g): testosterone — 0.292 to 0.322; progesterone — 42.63 to 60.01; prolactin — 344.6 to 475.4; estradiol — 431.2 to 847.9;

— minerals (mg %): К 0,50, Na 38, Ca 14, P 189, Mg 2, Fe 3.23, Mn 4.40, Zn 5.54, Cu 2, Cr, Co, Ni, Ag, Au, etc.;

— vitamins (water- and liposoluble): А 0.54 IU/g; xanthophyll 0.297mg %; β-carotene 0.426 IU/g; В2 0.739 mg %; D 950 IU/g; choline 442.8 mg %; nicotinic acid 15.8 mg %.

Package (number of tablets in one package): № 60, № 120.

Ingredients’ features

Drone brood homogenate helps to increase androgen levels that enhances bone remodeling, indirectly enhances osteoblasts’ activity and increases the number of osteocytes. Amino acids contained in drone brood homogenate participate in production of collagen that forms bone matrix.

Calcium citrate. “Osteomed Forte” contains calcium in form of calcium citrate that promotes the more complete and safe absorption of it from gastrointestinal tract. Furthermore, it helps to inhibit parathyroid hormone production and to prevent bone tissue resorption being the most efficient and safe form of calcium necessary for bone strengthening and increase of bone mineral density.

Vitamin D3 (cholecalciferol). Mechanism of intermolecular relationship of vitamin D3 is associated with activating vitamin D receptor, induction of transcription factors and nucleus receptors. The end effect of vitamin D3 is maintaining calcium homeostasis due to its participation in bone tissue formation, including control of cells’ growth, differentiation and apoptosis. Vitamin D3 is contributive to calcium, magnesium, and phosphorus absorption and responsible for reducing excretion of these minerals with urine through kidneys. It is necessary for normal mineralization and growth of bones. Vitamin D3 actively promotes the growth of skeleton, muscles, and mineralization of bones and teeth.

Vitamin В6 (pyridoxine hydrochloride) contributes to the absorption of magnesium from gastrointestinal tract, supplying cells with it, calcium absorption and its transportation through cell membranes, thus, preventing calcium metabolism disorders and providing its retention in new born osteocytes. Vitamin В6 also prevents lithiasis (stone formation) in renal pelvis and takes part in synthesis of female sex hormones.

Action

— regulates calcium-phosphorus metabolism due to the multi-level effect on all links of development of osteoporosis;

— has an anabolic effect on human connective tissues, especially, contributes to the birth of new bone cells, i.e. enhances;

— inhibits destruction of bone cells (antiresorptive effect);

— acts as donator of prohormones to provide safe normalization of hormonal status (that is especially important during menopause and post-menopause), restore bone tissue structure and increase its density;

— restorates bone tissue structure and increases its density when filling it with calcium and other necessary minerals and vitamins;

— enhances of secretion of collagen that participate in forming bone matrix;

—enhances accelerated consolidation of bones after fractures.

Indications:

–– for prevention and combined therapy of osteoporosis, osteopenia, and concomitant diseases, such as arthritis, arthrosis, osteochondrosis, periodontosis, and other pathologies of musculoskeletal system;

— as additional source of Са, vitamins D3, and В6;

— during rehabilitation after bone fractures.

Recommended for use as follows

Adults: 2 tablets 2 times a day. Preventive therapy: 2 tablets in the evening.

Course of supplementation: — 6 months (with 5–10-days pause after each month of treatment). The best way of intake is sublingual.

Dosage and regimen are developed on the basis of studies and prescribing practices of therapists and phytotherapists.